| 1 | 226* | G Fowler & D Lloyd | Lancashire v Warwickshire | 1982 | f34178 |
| 2 | 211 | KK Jennings & JJ Bohannon | Lancashire v Somerset | 2022 | f60915 |
| 3 | 258 | AN Petersen & AG Prince | Lancashire v Derbyshire | 2015 | f56405 |
| 4 | 470 | AI Kallicharran & GW Humpage | Warwickshire v Lancashire | 1982 | f34178 |
| 5 | 145* | Nottinghamshire v Lancashire | 1968 | f27347 | |
| 5 | 145 | LP Goldsworthy & JEK Rew | Somerset v Lancashire | 2022 | f60915 |
| 6 | 145 | Somerset v Lancashire | 1966 | f26388 | |
| 7 | 139* | DJ Vilas & JJ Bohannon | Lancashire v Worcestershire | 2018 | f58771 |
| 8 | 191 | AJA Wheater & MT Coles | Hampshire v Lancashire | 2013 | f54938 |
| 9 | 87 | R McLaren & TE Bailey | Lancashire v Middlesex | 2017 | f57922 |
| 10 | 122 | JP Crawley & AA Barnett | Lancashire v Somerset | 1994 | f41109 |