| 1 | 218 | AS Rollins & MB Loye | Northamptonshire v Zimbabweans | 2000 | a12816 |
| 2 | 245 | G Cook & RJ Bailey | Northamptonshire v Gloucestershire | 1987 | a5224 |
| 3 | 207* | AJ Lamb & RJ Bailey | Northamptonshire v Hampshire | 1985 | a4382 |
| 4 | 215 | DJG Sales & CJL Rogers | Northamptonshire v Yorkshire | 2006 | a17436 |
| 5 | 199 | C Munro & C de Grandhomme | New Zealand A v Northamptonshire | 2014 | a23444 |
| 6 | 167* | DJG Sales & JN Snape | Northamptonshire v Sri Lankans | 1998 | a11323 |
| 7 | 115 | DJG Sales & N Boje | Northamptonshire v Derbyshire | 2008 | a19072 |
| 8 | 113 | MP Maynard & AG Wharf | Glamorgan v Northamptonshire | 2004 | a15986 |
| 9 | 72 | RS Dravid & GI Maiden | Scotland v Northamptonshire | 2003 | a15243 |
| 10 | 50* | EE Hemmings & MK Bore | Nottinghamshire v Northamptonshire | 1979 | a2527 |