| 1 | 118 | KK Jennings & FH Allen | Lancashire v Nottinghamshire | 2021 | tt9716 |
| 2 | 160 | MB Loye & BJ Hodge | Lancashire v Durham | 2005 | tt218 |
| 3 | 128 | TC Smith & PJ Horton | Lancashire v Worcestershire | 2014 | tt4321 |
| 4 | 151* | SJ Croft & JP Faulkner | Lancashire v Derbyshire | 2015 | tt4955 |
| 5 | 107 | GJ Maxwell & DJ Vilas | Lancashire v Nottinghamshire | 2019 | tt8023 |
| 6 | 102* | A Javid & Mohammad Nabi | Leicestershire v Lancashire | 2018 | tt7090 |
| 7 | 81 | TH David & L Wood | Lancashire v Worcestershire | 2022 | tt10860 |
| 8 | 66* | CMW Read & RJ Sidebottom | Nottinghamshire v Lancashire | 2009 | tt1241 |
| 9 | 52 | LE Plunkett & BW Harmison | Durham v Lancashire | 2010 | tt1787 |
| 10 | 23* | TC Smith & G Keedy | Lancashire v Yorkshire | 2006 | tt413 |