| 173* | MJ Di Venuto | Derbyshire v Derbyshire Cricket Board | 2000 | a12784 |
| 172* | ARI Umeed | Somerset v Derbyshire | 2023 | a30168 |
| 158 | RK Rao | Sussex v Derbyshire | 1997 | a10641 |
| 157 | CM Gazzard | Somerset v Derbyshire | 2004 | a15899 |
| 155 | MS Wade | Australia A v Derbyshire | 2019 | a27431 |
| 153 | A Hill | Derbyshire v Cornwall | 1986 | a4901 |
| 152* | GH Roderick | Worcestershire v Derbyshire | 2024 | a31025 |