| 1 | 181 | G Clark & AZ Lees | Durham v Northamptonshire | 2025 | tt15514 |
| 2 | 141 | MD Stoneman & CS MacLeod | Durham v Derbyshire | 2016 | tt5859 |
| 3 | 126 | AD Hales & BM Duckett | Nottinghamshire v Durham | 2021 | tt9672 |
| 4 | 113 | CS MacLeod & PD Collingwood | Durham v Worcestershire | 2014 | tt4314 |
| 5 | 86 | OG Robinson & AJ Turner | Durham v Warwickshire | 2023 | tt12368 |
| 6 | 126* | CS MacLeod & JW Hastings | Durham v Northamptonshire | 2014 | tt4468 |
| 7 | 62 | CJ Green & GP Balderson | Lancashire v Durham | 2024 | tt13811 |
| 8 | 66 | JA Morkel & GR Breese | Durham v Warwickshire | 2010 | tt1817 |
| 9 | 37 | R Shepherd & JO Holder | West Indies v England | 2025 | tt15203 |
| 10 | 34* | OP Stone & Fazal Haque | Nottinghamshire v Durham | 2024 | tt13935 |