| 6-26 | MJ Leach | Somerset v Durham | 2024 | a31012 |
| 6-27 | PJ Franks | Nottinghamshire v Durham | 2000 | a12748 |
| 6-30 | SJE Brown | Durham v Northamptonshire | 1997 | a10457 |
| 6-51 | AW Laraman | Middlesex v Durham | 2000 | a12805 |
| 5-9 | DA Leatherdale | Worcestershire v Durham | 2002 | a14346 |
| 5-28 | GP Swann | England v Australia | 2009 | a19988 |
| 5-29 | AJ Hollioake | Surrey v Durham | 2000 | a12709 |
| 5-31 | VC Drakes | Nottinghamshire v Durham | 1999 | a12076 |
| 5-31 | C Rushworth | Durham v Nottinghamshire | 2012 | a21996 |
| 5-33 | PLS Gamage | Sri Lanka A v Durham | 2014 | a23409 |
| 5-33 | UT Yadav | Middlesex v Durham | 2022 | a29336 |
| 5-35 | GP Swann | Northamptonshire v Durham | 1999 | a11988 |
| 5-35 | Shoaib Akhtar | Durham v Somerset | 2003 | a15230 |
| 5-41 | GR Breese | Durham v Derbyshire | 2008 | a19009 |
| 5-42 | JEC Franklin | New Zealand v England | 2004 | a15961 |
| 5-42 | C Rushworth | Durham v Hampshire | 2013 | a22703 |
| 5-45 | RJ Bailey | Derbyshire v Durham | 2000 | a12676 |
| 5-46 | Z de Bruyn | Surrey v Durham | 2012 | a22083 |
| 5-48 | ML Lewis | Durham v Sussex | 2005 | a16595 |
| 5-48 | N Killeen | Durham v Gloucestershire | 2009 | a19822 |
| 5-49 | GR Breese | Durham v Worcestershire | 2007 | a18248 |
| 5-51 | HF Gurney | Nottinghamshire v Durham | 2016 | a24789 |