| 1 | 255 | MA Roseberry & S Hutton | Durham v Herefordshire | 1995 | a9297 |
| 2 | 211* | G Clark & SG Borthwick | Durham v Hampshire | 2021 | a28519 |
| 3 | 221 | A Habib & VJ Wells | Leicestershire v Durham | 1997 | a10485 |
| 4 | 208 | CT Bancroft & MJ Richardson | Durham v Northamptonshire | 2019 | a27266 |
| 5 | 186* | MW Goodwin & GW Flower | Zimbabwe v West Indies | 2000 | a12856 |
| 6 | 175 | JEC Franklin & SJ Adshead | Gloucestershire v Durham | 2009 | a19821 |
| 7 | 91 | KK Jennings & GR Breese | Durham v Sri Lanka A | 2014 | a23408 |
| 8 | 99 | AC Voges & PJ Franks | Nottinghamshire v Durham | 2012 | a21995 |
| 9 | 66 | TT Bresnan & A Shahzad | Yorkshire v Durham | 2008 | a18950 |
| 10 | 81 | LE Plunkett & SJ Harmison | Durham v Somerset | 2008 | a19077 |