| 131* | AJ Finch | Surrey v Sussex | 2018 | tt7043 |
| 121* | MM Ali | Worcestershire v Sussex | 2019 | tt8127 |
| 117 | MJ Prior | Sussex v Glamorgan | 2010 | tt1793 |
| 115* | DJ Malan | Middlesex v Sussex | 2015 | tt4935 |
| 112* | CD Nash | Sussex v Somerset | 2016 | tt5735 |
| 109 | JJ Roy | Surrey v Sussex | 2016 | tt5745 |
| 100* | RC Irani | Essex v Sussex | 2006 | tt433 |
| 100* | MW Goodwin | Sussex v Surrey | 2011 | tt2346 |
| 100* | SB Styris | Sussex v Gloucestershire | 2012 | tt3053 |
| 100 | DJ Willey | Northamptonshire v Sussex | 2015 | tt5121 |