| 1 | 198 | RS Vasconcelos & EN Gay | Northamptonshire v Lancashire | 2022 | a29397 |
| 2 | 151* | AN Petersen & LA Procter | Lancashire v Nottinghamshire | 2016 | a24774 |
| 3 | 136 | A Flintoff & NH Fairbrother | Lancashire v Durham | 2001 | a13621 |
| 4 | 72 | BT Slater & M Montgomery | Nottinghamshire v Lancashire | 2022 | a29421 |
| 5 | 66* | LD McManus & AH Miller | Northamptonshire v Lancashire | 2022 | a29397 |
| 6 | 82 | GID Lavelle & GP Balderson | Lancashire v Northamptonshire | 2022 | a29397 |
| 7 | 94 | SJ Croft & DJ Lamb | Lancashire v Nottinghamshire | 2022 | a29421 |
| 8 | 34 | SA Selwood & JID Kerr | Derbyshire v Lancashire | 2002 | a14403 |
| 9 | 130 | CP Schofield & GI Maiden | Lancashire v India A | 2003 | a15208 |
| 10 | 37* | IK Pathan & AM Salvi | India A v Lancashire | 2003 | a15208 |