| 131 | EN Gay | Northamptonshire v Lancashire | 2022 | a29398 |
| 125 | KK Jennings | Lancashire v Northamptonshire | 2022 | a29398 |
| 115* | SJ Croft | Lancashire v Nottinghamshire | 2022 | a29422 |
| 107* | KK Jennings | Lancashire v Kent | 2024 | a30997 |
| 105 | JJ Bohannon | Lancashire v Kent | 2023 | a30123 |
| 104 | RS Vasconcelos | Northamptonshire v Lancashire | 2022 | a29398 |
| 104 | BT Slater | Nottinghamshire v Lancashire | 2022 | a29422 |
| 100* | NH Fairbrother | Lancashire v Glamorgan | 1989 | a6093 |