| 200 | V Kohli | India v West Indies | 2016 | t2207 |
| 150 | CH Gayle | West Indies v New Zealand | 2012 | t2050 |
| 143 | IR Bell | England v West Indies | 2014/15 | t2157 |
| 140 | JM Bairstow | England v West Indies | 2021/22 | t2454 |
| 134 | KOA Powell | West Indies v New Zealand | 2012 | t2050 |
| 128 | RR Sarwan | West Indies v Australia | 2008 | t1877 |
| 126 | KC Brathwaite | West Indies v Sri Lanka | 2020/21 | t2417 |
| 123 | NE Bonner | West Indies v England | 2021/22 | t2454 |
| 122 | GS Ballance | England v West Indies | 2014/15 | t2157 |
| 121 | KC Brathwaite | West Indies v Bangladesh | 2018 | t2310 |
| 121 | Z Crawley | England v West Indies | 2021/22 | t2454 |
| 113 | SM Katich | Australia v West Indies | 2008 | t1877 |
| 113 | R Ashwin | India v West Indies | 2016 | t2207 |
| 113* | NE Bonner | West Indies v Sri Lanka | 2020/21 | t2416 |
| 112* | J Blackwood | West Indies v England | 2014/15 | t2157 |
| 110 | MJ Clarke | Australia v West Indies | 2008 | t1877 |
| 109 | JE Root | England v West Indies | 2021/22 | t2454 |
| 107* | S Chanderpaul | West Indies v Australia | 2008 | t1877 |
| 103* | JO Holder | West Indies v England | 2014/15 | t2157 |
| 103 | PN Silva | Sri Lanka v West Indies | 2020/21 | t2416 |
| 102 | AM Rahane | India v West Indies | 2019 | t2358 |