| 158 | ML Hayden | Australia v West Indies | 2006/07 | o2555 |
| 128 | D Ramdin | West Indies v England | 2013/14 | o3484 |
| 124* | LS Livingstone | England v West Indies | 2024/25 | o4792 |
| 117 | SD Hope | West Indies v England | 2024/25 | o4792 |
| 110 | SD Hope | West Indies v Sri Lanka | 2020/21 | o4276 |
| 109* | SD Hope | West Indies v England | 2023/24 | o4706 |
| 107 | JE Root | England v West Indies | 2013/14 | o3484 |
| 107 | EJG Morgan | England v West Indies | 2016/17 | o3845 |
| 106 | MJ Lumb | England v West Indies | 2013/14 | o3477 |
| 104 | KP Pietersen | England v Australia | 2006/07 | o2565 |
| 103 | E Lewis | West Indies v Sri Lanka | 2020/21 | o4277 |
| 102* | SP Fleming | New Zealand v Bangladesh | 2006/07 | o2561 |
| 102 | HM Amla | South Africa v West Indies | 2010 | o2979 |
| 102 | AB de Villiers | South Africa v West Indies | 2010 | o2979 |
| 102 | DM Bravo | West Indies v Sri Lanka | 2020/21 | o4278 |