| 120* | F du Plessis | St Lucia Kings v St Kitts and Nevis Patriots | 2021 | tt9969 |
| 116 | CH Gayle | Jamaica Tallawahs v St Kitts and Nevis Patriots | 2019 | tt8133 |
| 106* | MN Samuels | Antigua Hawksbills v Guyana Amazon Warriors | 2014 | tt4491 |
| 105* | C Hemraj | Guyana Amazon Warriors v Barbados Royals | 2021 | tt9970 |
| 102* | E Lewis | St Kitts and Nevis Patriots v Trinbago Knight Riders | 2021 | tt9994 |
| 100 | AD Russell | Jamaica Tallawahs v Trinbago Knight Riders | 2016 | tt5874 |