| 169 | D Ramdin | West Indies v Bangladesh | 2014 | a23514 |
| 128* | JH Kallis | South Africa v Netherlands | 2006/07 | a18095 |
| 124 | DM Bravo | West Indies v Bangladesh | 2014 | a23514 |
| 123 | BJ Hodge | Australia v Netherlands | 2006/07 | a18106 |
| 115* | RR Sarwan | West Indies v India | 2006 | a17450 |
| 113 | RT Ponting | Australia v Scotland | 2006/07 | a18089 |
| 113 | KR Mayers | Barbados v Leeward Islands | 2019/20 | a27761 |
| 113 | SE Rutherford | West Indies v Bangladesh | 2024/25 | a31304 |
| 110 | LRPL Taylor | New Zealand v West Indies | 2012 | a22039 |
| 110 | HM Amla | South Africa v West Indies | 2016 | a24793 |
| 109 | DA Warner | Australia v South Africa | 2016 | a24767 |
| 105 | DC Thomas | Leeward Islands v Combined Campuses and Colleges | 2019/20 | a27743 |
| 104* | AA Jangoo | West Indies v Bangladesh | 2024/25 | a31306 |
| 103* | AB Fudadin | Guyana v Combined Campuses and Colleges | 2015/16 | a24566 |
| 103 | Tamim Iqbal | Bangladesh v West Indies | 2018 | a26543 |
| 101 | ML Hayden | Australia v South Africa | 2006/07 | a18134 |
| 101* | KY Ottley | Barbados v Combined Campuses and Colleges | 2019/20 | a27787 |
| 100* | R Powell | Jamaica v Canada | 2019/20 | a27776 |