| 140 | HM Amla | South Africa v Bangladesh | 2008/09 | o2772 |
| 129 | JP Duminy | South Africa v Zimbabwe | 2010/11 | o3061 |
| 123* | MS Atapattu | Sri Lanka v South Africa | 2002/03 | o1907 |
| 121* | NFI McCallum | Scotland v Ireland | 2008/09 | o2830 |
| 113 | T Bavuma | South Africa v Ireland | 2016/17 | o3781 |
| 109 | AB de Villiers | South Africa v Zimbabwe | 2010/11 | o3061 |
| 104 | SR Tendulkar | India v Zimbabwe | 1996/97 | o1175 |
| 103* | T Taibu | Zimbabwe v South Africa | 2009/10 | o2926 |
| 101 | WTS Porterfield | Ireland v Scotland | 2008/09 | o2830 |