| 6-43 | Gulbadeen Naib | Afghanistan v Ireland | 2019 | o4141 |
| 5-21 | TJ Murtagh | Ireland v Zimbabwe | 2019 | o4185 |
| 4-12 | VD Philander | South Africa v Ireland | 2007 | o2591 |
| 4-12 | Junaid Khan | Pakistan v Ireland | 2011 | o3157 |
| 4-19 | AC Botha | Ireland v Kenya | 2008 | o2751 |
| 4-19 | MR Adair | Ireland v Afghanistan | 2019 | o4140 |
| 4-21 | Rashid Khan | Afghanistan v Ireland | 2016 | o3763 |
| 4-24 | GH Dockrell | Ireland v Scotland | 2013 | o3411 |
| 4-26 | DT Johnston | Ireland v England | 2009 | o2878 |
| 4-29 | B Muzarabani | Zimbabwe v Ireland | 2021 | o4319 |
| 4-30 | TJ Murtagh | Ireland v Afghanistan | 2018 | o4033 |
| 4-31 | TJ Murtagh | Ireland v Afghanistan | 2018 | o4032 |
| 4-35 | Saeed Ajmal | Pakistan v Ireland | 2011 | o3158 |
| 4-43 | SF Mire | Zimbabwe v Ireland | 2019 | o4185 |
| 4-45 | KJ O'Brien | Ireland v Afghanistan | 2016 | o3761 |
| 4-59 | Shafiul Islam | Bangladesh v Ireland | 2010 | o3028 |
| 4-59 | BJ McCarthy | Ireland v Afghanistan | 2016 | o3761 |