| 160* | EC Joyce | Ireland v Afghanistan | 2016 | a24823 |
| 128 | LI Georgeson | Northern Knights v Munster Reds | 2021 | a28441 |
| 125 | MK Commins | Munster Reds v Northern Knights | 2021 | a28441 |
| 120* | RR Hendricks | South Africa A v Ireland | 2012 | a22107 |
| 117 | AR McBrine | North West Warriors v Northern Knights | 2022 | a29077 |
| 115* | EC Joyce | Ireland v United Arab Emirates | 2005 | a16707 |
| 114 | DS Smith | West Indies A v Ireland | 2010 | a20629 |
| 114 | MK Commins | Munster Reds v Northern Knights | 2023 | a30018 |
| 113 | ME Trescothick | England v Ireland | 2006 | a17485 |
| 111 | SMA Priyanjan | Sri Lanka A v Ireland | 2014 | a23417 |
| 110* | WTS Porterfield | North West Warriors v Northern Knights | 2018 | a26450 |
| 109 | PR Stirling | Ireland v Pakistan | 2011 | a21390 |
| 109 | SW Poynter | Ireland v Sri Lanka A | 2014 | a23413 |
| 108 | WTS Porterfield | Ireland v Bangladesh | 2010 | a20670 |
| 107 | SM Lynch | Leinster Lightning v Northern Knights | 2023 | a30189 |
| 105* | EC Joyce | Ireland v Afghanistan | 2016 | a24817 |
| 104* | BF Calitz | Northern Knights v Munster Reds | 2024 | a30911 |
| 103 | EC Joyce | Ireland v Bermuda | 2005 | a16694 |
| 102* | JL Denly | Kent v Ireland | 2007 | a18201 |
| 101 | Mohammad Shahzad | Afghanistan v Ireland | 2019 | a27391 |
| 100 | Junaid Siddique | Bangladesh v Ireland | 2010 | a20670 |